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KMID : 0882420160900060550
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Korean Journal of Medicine
2016 Volume.90 No. 6 p.550 ~ p.553
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Acute Kidney Injury due to Rbadomyolysis Complicated with Zolpidem Overdose
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Kim Hong-Ik
Cho Seong-Ho
Hong Hyo-Lim
Lee In-Hee
Ahn Ki-Sung
Kang Gun-Woo
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Abstract
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Zolpidem (Stilnox®, Handok, Seoul, Korea) is a hypnotic imidazopyridine that is often used to treat insomnia because it has less abuse and addiction potential than benzodiazepines. Its side effects include headache, dizziness, and nausea, but these are mild. Zolpidem intoxication rarely has severe complications. Here, we report a case of acute kidney injury due to rhabdomyolysis related to zolpidem. A 51-year-old man was admitted with drowsy mentality after taking an overdose of zolpidem in a suicide attempt. Laboratory findings showed a blood urea nitrogen of 59.9 mg/dL, serum creatinine of 5.8 mg/dL, and creatine phosphokinase of 16,210 IU/L. Acute kidney injury associated with rhabdomyolysis complicating zolpidem intoxication was diagnosed. The patient was managed with hemodialysis and recovered completely in terms of renal function and muscle enzyme levels.
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KEYWORD
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Zolpidem, Acute kidney injury, Rhabdomyolysis
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